Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atoh1tm4.1Hzo
Name:	atonal bHLH transcription factor 1; targeted mutation 4.1, Huda Y Zoghbi
MGI ID:	MGI:4418332
Synonyms:	Atoh1EGFP, Atoh1-EGFP, Math1m1GFP
Gene:	Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance:	Atoh1tm4.1Hzo page

Germline Transmission:	Earliest citation of germline transmission: J:155760
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: An EGFP sequence was fused to the 3' end of the coding sequence and was followed by an frt flanked PGK-neomycin selection cassette. The selection cassette was subsequently excised by crossing to mice carrying Gt(ROSA)26Sortm1(FLP1)Dym. (J:155760)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

30 assay results 4 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:	36 strains or lines available

Original:	J:155760 Rose MF, et al., Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54
All:	43 reference(s)