About   Help   FAQ
Rgs5tm1Rgan
Targeted Allele Detail
Summary
Symbol: Rgs5tm1Rgan
Name: regulator of G-protein signaling 5; targeted mutation 1, Ruth Ganss
MGI ID: MGI:3796066
Gene: Rgs5  Location: Chr1:169483070-169523367 bp, + strand  Genetic Position: Chr1, 76.84 cM, cytoband H2
Alliance: Rgs5tm1Rgan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136259
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and an frt-flanked neo cassette was inserted downstream of exon 1. Germ line, flp-mediated recombination was used to remove the neo cassette. (J:136259)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rgs5 Mutation:  21 strains or lines available
References
Original:  J:136259 Hamzah J, et al., Vascular normalization in Rgs5-deficient tumours promotes immune destruction. Nature. 2008 May 15;453(7193):410-4
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory