Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atp2a2tm1.1Iemr
Name:	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2; targeted mutation 1.1, Ole Sejersted
MGI ID:	MGI:4415164
Synonyms:	Atp2a2tm1.1Kba, Sercaflox
Gene:	Atp2a2  Location: Chr5:122591576-122640288 bp, - strand  Genetic Position: Chr5, 62.38 cM, cytoband F
Alliance:	Atp2a2tm1.1Iemr page

Germline Transmission:	Earliest citation of germline transmission: J:155628
Parent Cell Line:	E14.1a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 3. Cre mediated recombination removes the neo cassette leaving exons 2 and 3 floxed. (J:155628)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp2a2 Mutation:	76 strains or lines available

Original:	J:155628 Andersson KB, et al., Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models. Cell Calcium. 2009 Sep;46(3):219-25
All:	18 reference(s)