Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Cdx2tm1.1Lhn
Name:	caudal type homeobox 2; targeted mutation 1.1, David Lohnes
MGI ID:	MGI:4415130
Synonyms:	Cdx2f
Gene:	Cdx2  Location: Chr5:147237710-147244059 bp, - strand  Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
Alliance:	Cdx2tm1.1Lhn page

Germline Transmission:	Earliest citation of germline transmission: J:154904
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 2. Cre mediated recombination removed the neo cassette leaving exon 2 floxed. (J:154904)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

List all tumor models in MMHCdb carrying Cdx2tm1.1Lhn

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdx2 Mutation:	22 strains or lines available

Original:	J:154904 Savory JG, et al., Cdx2 regulation of posterior development through non-Hox targets. Development. 2009 Dec;136(24):4099-110
All:	13 reference(s)