About   Help   FAQ
Wnt8btm1Jmas
Targeted Allele Detail
Summary
Symbol: Wnt8btm1Jmas
Name: wingless-type MMTV integration site family, member 8B; targeted mutation 1, John Mason
MGI ID: MGI:4414945
Gene: Wnt8b  Location: Chr19:44481912-44502712 bp, + strand  Genetic Position: Chr19, 37.98 cM
Alliance: Wnt8btm1Jmas page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155332
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 4 and 5 and most of the coding region contained within exon 6 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR and in situ hybridization. (J:155332)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt8b Mutation:  17 strains or lines available
References
Original:  J:155332 Fotaki V, et al., Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn. 2010 Jan;239(1):284-96
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory