Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nkx6-2tm1(cre/ERT2)Fsh
Name:	NK6 homeobox 2; targeted mutation 1, Gordon Fishell
MGI ID:	MGI:4412372
Synonyms:	Nkx6-2CreER, Nkx6-2tm1.1(cre/ERT2)Fsh
Gene:	Nkx6-2  Location: Chr7:139159292-139162713 bp, - strand  Genetic Position: Chr7, 84.57 cM
Alliance:	Nkx6-2tm1(cre/ERT2)Fsh page

Germline Transmission:	Earliest citation of germline transmission: J:155164
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutations:    Insertion, Intragenic deletion   Nkx6-2tm1(cre/ERT2)Fsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nkx6-2 (MGI:1352738)     Exons 1 and 2 were replaced with a cre/ERT2 fusion and floxed self-excising neo cassette. (J:155164)

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx6-2 (mouse) Summary of all recombinase alleles driven by Nkx6-2. Alliance mouse Nkx6-2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nkx6-2 Mutation:	16 strains or lines available

Original:	J:155164 Sousa VH, et al., Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex. 2009 Jul;19 Suppl 1:i1-10
All:	2 reference(s)