Summary | Mutation origin | Mutation description | Expression | Tumor data | Find Mice (IMSR) | References

Symbol:	Arid1atm1.1Zhwa
Name:	AT-rich interaction domain 1A; targeted mutation 1.1, Zhong Wang
MGI ID:	MGI:3789986
Synonyms:	BAF250af
Gene:	Arid1a  Location: Chr4:133406319-133484080 bp, - strand  Genetic Position: Chr4, 66.25 cM
Alliance:	Arid1atm1.1Zhwa page

Germline Transmission:	Earliest citation of germline transmission: J:134633
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An frt-flanked betageo cassette with a 3' loxP site and a 5' SV40-polyA tail was inserted downstream of exon 8 and an additional loxP site was inserted upstream of exon 8. Transient flp expression in ES cells was used to remove the betageo cassette and leave exon 8 floxed. (J:134633)

In Mice Carrying this Mutation:

8 assay results 5 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Arid1atm1.1Zhwa

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arid1a Mutation:	179 strains or lines available

Original:	J:134633 Gao X, et al., ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6656-61
All:	49 reference(s)