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Slc45a2uw-4Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Slc45a2uw-4Btlr
Name: solute carrier family 45, member 2; underwhite 4 Bruce Beutler
MGI ID: MGI:3784986
Synonyms: Slc45a2m4Btlr, sweater
Gene: Slc45a2  Location: Chr15:11000721-11029233 bp, + strand  Genetic Position: Chr15, 5.4 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation corresponds to an A-to-C transversion at nucleotide position 794 of the gene (Genbank: NM_053077), in the third of 7 exons, resulting in replacement of histidine at amino acid postion 233 by proline (H233P) in the sixth transmembrane domain of the protein. (J:133631)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:  42 strains or lines available
References
Original:  J:133631 Blasius A, et al., Sweater is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory