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Gt(ROSA)26Sortm2.1(sb11)Njen
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm2.1(sb11)Njen
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Nancy A Jenkins
MGI ID: MGI:4367092
Synonyms: RosaSBase1loxP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm2.1(sb11)Njen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153656
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J x 129
Mutation
description
Allele Type:    Targeted (Transposase)
Mutation:    Insertion
 
Mutation detailsGerm line, cre mediated removal of the floxed EGFP and STOP cassette allows for expression of sleeping beauty (sb11) transposase. (J:153656)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Gt(ROSA)26Sortm2.1(sb11)Njen
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:153656 Dupuy AJ, et al., A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Res. 2009 Oct 15;69(20):8150-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory