Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pnpi
Name:	purine-nucleoside phosphorylase; NP-1I
MGI ID:	MGI:3777978
Synonyms:	Np-1i
Gene:	Pnp  Location: Chr14:51181760-51190869 bp, + strand  Genetic Position: Chr14, 26.31 cM, cytoband B-C1
Alliance:	Pnpi page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This allele was identified in the progeny of a cross between ENU mutagenized C57BL/6J males and C3H/HeHa females. A G to A transition occurred at nucleotide 682 resulting in an A228T amino acid change in the resulting protein. This is identical to the change in Pnp1. (J:522, J:39328)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pnp Mutation:	29 strains or lines available

Original:	J:522 Snyder FF, Genetic models of purine nucleoside phosphorylase deficiency in the mouse. Adv Exp Med Biol. 1991;309B:137-40
All:	2 reference(s)