Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxc8tm3(Hoxc9)Jepl
Name:	homeobox C8; targeted mutation 3, Jeh-Ping Liu
MGI ID:	MGI:4365796
Synonyms:	Hoxc8-c9F-GFP
Gene:	Hoxc8  Location: Chr15:102899039-102902543 bp, + strand  Genetic Position: Chr15, 58.05 cM
Alliance:	Hoxc8tm3(Hoxc9)Jepl page

Germline Transmission:	Earliest citation of germline transmission: J:153560
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted into exon 1 upstream of the initiation codon and a cassette containing a 5' loxP site, the Hoxc9 coding region, intron 2 sequence with flanking splice acceptor and donor sites, an IRES, a eGFP gene, an additional copy of the 3'UTR, and a neo resistance gene was inserted downstream of the 3'UTR. (J:153560)

Generation of the Hoxc8tm3(Hoxc9)Jepl and Hoxc8tm4(Hoxc9)Jepl alleles

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxc8 Mutation:	8 strains or lines available

Original:	J:153560 Blackburn J, et al., Generation of conditional Hoxc8 loss-of-function and Hoxc8-->Hoxc9 replacement alleles in mice. Genesis. 2009 Jul 20;47(10):680-687
All:	1 reference(s)