Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Arid3atm1a(KOMP)Wtsi
Name:	AT-rich interaction domain 3A; targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID:	MGI:4364761
Gene:	Arid3a  Location: Chr10:79762877-79790852 bp, + strand  Genetic Position: Chr10, 39.72 cM
Alliance:	Arid3atm1a(KOMP)Wtsi page
IMPC:	Arid3a gene page

Mutant Cell Lines:	EPD0089_4_D07, EPD0089_4_E09
Germline Transmission:	Earliest citation of germline transmission: J:204812
Parent Cell Line:	JM8.F6 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter) Mutation:    Insertion     Vector: L1L2_gt0   Mutation details: The L1L2_gt0 cassette was inserted at position 79781829 of Chromosome 10 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 79782681. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:148605, J:173534)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Arid3a Mutation:	20 strains or lines available

Original:	J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:	4 reference(s)