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Ldhaa-m3Neu
Chemically induced Allele Detail
Summary
Symbol: Ldhaa-m3Neu
Name: lactate dehydrogenase A; mutation 3, Neuherberg
MGI ID: MGI:3776263
Synonyms: Ldh13Neu, LDH 9546
Gene: Ldha  Location: Chr7:46491698-46505051 bp, + strand  Genetic Position: Chr7, 30.6 cM
Alliance: Ldhaa-m3Neu page
Mutation
origin
Strain of Origin:  (102/El x C3H/El)F1
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Undefined
 
Mutation detailsENU mutagenesis resulted in a defect that caused a 42% to 50% reduction of enzyme activity in heterozygous mice. (J:1072)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ldha Mutation:  34 strains or lines available
References
Original:  J:15477 Charles DJ, et al., Linear dose-response relationship of erythrocyte enzyme-activity mutations in offspring of ethylnitrosourea-treated mice. Mutat Res. 1987 Jan;176(1):81-91
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory