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a5mnu
Chemically induced Allele Detail
Summary
Symbol: a5mnu
Name: nonagouti; nonagouti 5methylnitrosourea
MGI ID: MGI:1856427
Gene: a  Location: Chr2:154792519-154892932 bp, + strand  Genetic Position: Chr2, 76.83 cM
Alliance: a5mnu page
Mutation
origin
Strain of Origin:  (101/H x C3H/HeH)F1
Mutation
description
Allele Type:    Chemically induced (other)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele comprises a 2.8 kb deletion. The deletion includes 129 bp that also are deleted from the distal breakpoint of the allele ajIs(17;In2)1Gso. In neonatal skin a transcript is present at wild-type levels, but is decreased in size to an extent that is consistent with a deletion of the third exon of nonagouti. (J:3523, J:16567)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any a Mutation:  463 strains or lines available
Notes
This allele was induced by methylnitrosourea (MNU) in spermatogonia. Homozygotes are jet black in color (J:16567).
References
Original:  J:16567 Bultman SJ, et al., Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8062-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory