Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bhlhe40tm1.1Rhli
Name:	basic helix-loop-helix family, member e40; targeted mutation 1.1, Robert H Lipsky
MGI ID:	MGI:3775803
Gene:	Bhlhe40  Location: Chr6:108637590-108643886 bp, + strand  Genetic Position: Chr6, 49.85 cM, cytoband E-F1
Alliance:	Bhlhe40tm1.1Rhli page

Germline Transmission:	Earliest citation of germline transmission: J:131834
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Germ-line cre-mediated recombination was used to remove exons 1 through 4. The absence of transcript was confirmed by RT-PCR on hippocampus extracts. (J:131834)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bhlhe40 Mutation:	50 strains or lines available

Original:	J:131834 Jiang X, et al., BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. J Neurosci. 2008 Jan 30;28(5):1118-30
All:	4 reference(s)