Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ush1gtm1.1Ugds
Name:	USH1 protein network component sans; targeted mutation 1.1, Unite de Genetique des Deficits Sensoriels
MGI ID:	MGI:4361359
Synonyms:	Ush1gfl
Gene:	Ush1g  Location: Chr11:115206018-115212867 bp, - strand  Genetic Position: Chr11, 80.84 cM
Alliance:	Ush1gtm1.1Ugds page

Germline Transmission:	Earliest citation of germline transmission: J:171218
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S1/SvImJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:171218)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ush1g Mutation:	16 strains or lines available

Original:	J:171218 Caberlotto E, et al., Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5825-30
All:	1 reference(s)