Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Kif7tm1Lex
Name:	kinesin family member 7; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:4360052
Gene:	Kif7  Location: Chr7:79347846-79365468 bp, - strand  Genetic Position: Chr7, 45.09 cM, cytoband D2
Alliance:	Kif7tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:152551
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with a lacZ gene and neo cassette. This insertion deletes the ATG initiation codon and 109 amino acids. (J:152551)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Kif7 Mutation:	39 strains or lines available

Original:	J:152551 Endoh-Yamagami S, et al., The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol. 2009 Aug 11;19(15):1320-6
All:	3 reference(s)