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Targeted Allele Detail
Symbol: Pou3f2tm1Mejr
Name: POU domain, class 3, transcription factor 2; targeted mutation 1, Dies Meijer
MGI ID: MGI:4359591
Synonyms: Brn-2flox
Gene: Pou3f2  Location: Chr4:22482780-22488366 bp, - strand  Genetic Position: Chr4, 9.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:83739
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsHomologous recombination was used to insert a loxP site 5' to the Pou3f2 and a frt-flanked neomycin gene driven by a thymidine kinase promoter and second loxP site followed by an EGFP gene, inserted into the 3' UTR. (J:83739)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f2 Mutation:  3 strains or lines available
Original:  J:83739 Jaegle M, et al., The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev. 2003 Jun 1;17(11):1380-91
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory