Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pou3f2tm1Mejr
Name:	POU domain, class 3, transcription factor 2; targeted mutation 1, Dies Meijer
MGI ID:	MGI:4359591
Synonyms:	Brn-2flox
Gene:	Pou3f2  Location: Chr4:22482780-22488366 bp, - strand  Genetic Position: Chr4, 9.73 cM
Alliance:	Pou3f2tm1Mejr page

Germline Transmission:	Earliest citation of germline transmission: J:83739
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Homologous recombination was used to insert a loxP site 5' to the Pou3f2 and a frt-flanked neomycin gene driven by a thymidine kinase promoter and second loxP site followed by an EGFP gene, inserted into the 3' UTR. (J:83739)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f2 Mutation:	19 strains or lines available

Original:	J:83739 Jaegle M, et al., The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev. 2003 Jun 1;17(11):1380-91
All:	2 reference(s)