About   Help   FAQ
Pou3f2tm1Mejr
Targeted Allele Detail
Nomenclature
Symbol: Pou3f2tm1Mejr
Name: POU domain, class 3, transcription factor 2; targeted mutation 1, Dies Meijer
MGI ID: MGI:4359591
Synonyms: Brn-2flox
Gene: Pou3f2  Location: Chr4:22482780-22488366 bp, - strand  Genetic Position: Chr4, 9.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83739
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsHomologous recombination was used to insert a loxP site 5' to the Pou3f2 and a frt-flanked neomycin gene driven by a thymidine kinase promoter and second loxP site followed by an EGFP gene, inserted into the 3' UTR. (J:83739)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f2 Mutation:  3 strains or lines available
References
Original:  J:83739 Jaegle M, et al., The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev. 2003 Jun 1;17(11):1380-91
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory