Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcl11atm1.1Pwt
Name:	BCL11 transcription factor A; targeted mutation 1.1, Philip W Tucker
MGI ID:	MGI:4358088
Gene:	Bcl11a  Location: Chr11:24028056-24124123 bp, + strand  Genetic Position: Chr11, 14.41 cM
Alliance:	Bcl11atm1.1Pwt page

Germline Transmission:	Earliest citation of germline transmission: J:151995
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Mice containing the floxed Bcl11atm1Pwt allele were crossed with Gata1-cre mice to create a null allele in the germline. No protein from the locus was detected in immunoblot analysis of liver extracts from homozygote E18.5 embryos. (J:151995)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11a Mutation:	42 strains or lines available

Original:	J:151995 Sankaran VG, et al., Developmental and species-divergent globin switching are driven by BCL11A. Nature. 2009 Aug 27;460(7259):1093-7
All:	3 reference(s)