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Ay-Jkn
Spontaneous Allele Detail
Summary
Symbol: Ay-Jkn
Name: nonagouti; dominant yellow
MGI ID: MGI:3774267
Synonyms: Ay-Jkn1
Gene: a  Location: Chr2:154792519-154892932 bp, + strand  Genetic Position: Chr2, 76.83 cM
Alliance: Ay-Jkn page
Mutation
origin
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Spontaneous (Constitutively active)
Mutation:    Other
 
Mutation detailsA spontaneous mutation fusing the promoter and 5'-UTR of Raly to the agouti gene leads to constitutive expression of the agouti gene. Details will be reported in a manuscript currently in preparation by PS Budd and IJ Jackson. (J:129904)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any a Mutation:  463 strains or lines available
References
Original:  J:129904 Jackson IJ, et al., Humanized MC1R transgenic mice reveal human specific receptor function. Hum Mol Genet. 2007 Oct 1;16(19):2341-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory