Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rr96tm1.1Yzo
Name:	regulatory region 96; targeted mutation 1.1, Yong-Rui Zou
MGI ID:	MGI:3774142
Synonyms:	Cd4deltaLS, Cd4tm1.1Yzo, sil-
Gene:	Rr96  Location: unknown  Genetic Position: Chr6, Syntenic
Alliance:	Rr96tm1.1Yzo page

Germline Transmission:	Earliest citation of germline transmission: J:130559
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Modified regulatory region) Mutation:    Intragenic deletion   Mutation details: A loxP site was inserted downstream of Cd4 intronic silencer S4 and a loxP site flanked neomycin resistance gene cassette upstream. Cre-mediated recombination was used to delete the silencer and the neo cassette. (J:130559)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr96 Mutation:	0 strains or lines available

Original:	J:130559 Zou YR, et al., Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage. Nat Genet. 2001 Nov;29(3):332-6
All:	4 reference(s)