Fgf21tm1Djm
Targeted Allele Detail
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| Symbol: |
Fgf21tm1Djm |
| Name: |
fibroblast growth factor 21; targeted mutation 1, David J Mangelsdorf |
| MGI ID: |
MGI:4354160 |
| Synonyms: |
Fgf21loxP |
| Gene: |
Fgf21 Location: Chr7:45263314-45264914 bp, - strand Genetic Position: Chr7, 29.38 cM, cytoband B2
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| Alliance: |
Fgf21tm1Djm page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:150831
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Conditional ready, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 3.
(J:150831)
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Generation of the Fgf21tm1Djm and Fgf21tm1.1Djm alleles |
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Fgf21 Mutation: |
22 strains or lines available
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| Original: |
J:150831 Potthoff MJ, et al., FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10853-8 |
| All: |
7 reference(s) |
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Analysis Tools
