Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cfitm1Mcp
Name:	complement component factor i; targeted mutation 1, Matthew C Pickering
MGI ID:	MGI:3773693
Gene:	Cfi  Location: Chr3:129630432-129668978 bp, + strand  Genetic Position: Chr3, 59.21 cM
Alliance:	Cfitm1Mcp page

Germline Transmission:	Earliest citation of germline transmission: J:131403
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 4 was replaced with a neo cassette. The absence of protein was confrirmed by western blot analysis on serum extracts. (J:131403)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cfi Mutation:	44 strains or lines available

Original:	J:131403 Rose KL, et al., Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest. 2008 Feb;118(2):608-18
All:	2 reference(s)