Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Plcg2tm1.1Kuro
Name:	phospholipase C, gamma 2; targeted mutation 1.1, Tomohiro Kurosaki
MGI ID:	MGI:3773674
Synonyms:	PLCgamma2-
Gene:	Plcg2  Location: Chr8:118225030-118361881 bp, + strand  Genetic Position: Chr8, 64.26 cM
Alliance:	Plcg2tm1.1Kuro page

Germline Transmission:	Earliest citation of germline transmission: J:131161
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     The exon encoding the PIP2 binding site was removed by cre-mediated recombination. (J:63744)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plcg2 Mutation:	74 strains or lines available

Original:	J:131161 Xu S, et al., Phospholipase Cgamma2 dosage is critical for B cell development in the absence of adaptor protein BLNK. J Immunol. 2006 Apr 15;176(8):4690-8
All:	8 reference(s)