Phb1Gt(XT0035)Wtsi
Gene trapped Allele Detail
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| Symbol: |
Phb1Gt(XT0035)Wtsi |
| Name: |
prohibitin 1; gene trap XT0035, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:3771851 |
| Synonyms: |
PHB- |
| Gene: |
Phb1 Location: Chr11:95557783-95571599 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
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| Alliance: |
Phb1Gt(XT0035)Wtsi page
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| Mutant Cell Line: |
XT0035 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:130064
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| Parent Cell Line: |
E14TG2a.4 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Project Collection: |
Sanger Inst. Gene Trap Res.
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| Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
| Mutation: |
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Insertion of gene trap vector
Vector: pGT0lxf
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Mutation details: The gene trap containing the En2 intron 1, a splice acceptor and a beta-geo cassette with a poly adenylation signal was inserted into exon 7. Decreased protein expression was confirmed in heterozygote epithelial cells by western blot analysis.
(J:130064)
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| Sequence Tags: |
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Sequence tag details (1 tag)
| Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Phb1 Mutation: |
23 strains or lines available
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| Original: |
J:130064 He B, et al., A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb;22(2):344-60 |
| All: |
2 reference(s) |
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Analysis Tools
