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Leprdb-9J
Spontaneous Allele Detail
Summary
Symbol: Leprdb-9J
Name: leptin receptor; diabetes 9 Jackson
MGI ID: MGI:3770610
Synonyms: fuldib
Gene: Lepr  Location: Chr4:101574601-101672549 bp, + strand  Genetic Position: Chr4, 46.96 cM
Alliance: Leprdb-9J page
Mutation
origin
Strain of Origin:  mixed
Mutation
description
Allele Type:    Spontaneous
Mutation:    Undefined
 
Mutation detailsThis mutation was shown to be an allele of the leptin receptor gene by its failure to complement the original diabetes mutation, Leprdb.
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lepr Mutation:  121 strains or lines available
Notes
This mutation arose spontaneously in mice of a mixed genetic background (~46% C57BL/6, ~50% SWR, and ~3% CBA estimated from the breeding records).
References
Original:  J:129982 Naggert JK, et al., A new spontaneous obesity mutation, fuldib/diabetes 9 Jackson, is a allele of the leptin receptor gene. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory