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Gabrb3tm2Geh
Targeted Allele Detail
Summary
Symbol: Gabrb3tm2Geh
Name: GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3; targeted mutation 2, Gregg E Homanics
MGI ID: MGI:3767246
Synonyms: beta3Fneo
Gene: Gabrb3  Location: Chr7:57240266-57478550 bp, + strand  Genetic Position: Chr7, 33.53 cM
Alliance: Gabrb3tm2Geh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:127877
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 3 was flanked with loxP sites. An Frt-flanked neomycin resistance gene was also inserted 3' to exon 3. (J:127877)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gabrb3 Mutation:  30 strains or lines available
References
Original:  J:127877 Ferguson C, et al., New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout. BMC Neurosci. 2007;8:85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory