Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Gt(ROSA)26Sortm2.1(Mirn150)Rsky
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Klaus Rajewsky
MGI ID:	MGI:3763537
Synonyms:	Gt(ROSA)26Sortm2.1(Mir150)Rsky, mir150 Tg
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm2.1(Mirn150)Rsky page

Germline Transmission:	Earliest citation of germline transmission: J:127234
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inserted expressed sequence) Mutation:    Insertion   Gt(ROSA)26Sortm2.1(Mirn150)Rsky expresses 1 gene Knock-in expresses: Organism Expressed Gene Note mouse Mir150 (MGI:2676835)   Mutation details: Gt(ROSA)26Sortm2(Mirn150)Rsky mice were crossed to Tg(ACTFLPe)9205Dym mice to excise the frt-flanked IRES-EGFP cassette, producing mice slightly over-expressing Mirn150 (from the CAG promoter) in thymocytes. It is also possible to generate this allele from allele Gt(ROSA)26Sortm14.1(Mirn150)Rsky. (J:127234)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:127234 Xiao C, et al., MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell. 2007 Oct 5;131(1):146-59
All:	2 reference(s)