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Targeted Allele Detail
Symbol: Tead2tm1Mldp
Name: TEA domain family member 2; targeted mutation 1, Melvin DePamphilis
MGI ID: MGI:3763365
Gene: Tead2  Location: Chr7:45215753-45233636 bp, + strand  Genetic Position: Chr7, 29.19 cM, cytoband B5
Germline Transmission:  Earliest citation of germline transmission: J:127233
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Conditional ready, Modified regulatory region, No functional change)
Mutation:    Insertion
Mutation detailsA neo cassette flanked by frt sites and containing a 3' loxP site was inserted downstream of exon 3 and an additional loxP site was inserted downstream of exon 1 enclosing a gene enhancer as well as exons 2 and 3. Insertion was confirmed by Southern blot analysis. (J:127233)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tead2 Mutation:  20 strains or lines available
Original:  J:127233 Kaneko KJ, et al., Transcription factor TEAD2 is involved in neural tube closure. Genesis. 2007 Sep;45(9):577-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory