Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Gt(ROSA)26Sor-EGFP)I1Able
Name:	transgene insertion I1, Andrew B Leiter
MGI ID:	MGI:3763223
Synonyms:	ROSA26-EGFP, ROSA26-EGFP BAC
Transgene:	Tg(Gt(ROSA)26Sor-EGFP)I1Able  Location: unknown
Alliance:	Tg(Gt(ROSA)26Sor-EGFP)I1Able page

Strain of Origin:

C57BL/6 x (C57BL/6 x DBA/2)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: The bacterial artificial chromosome (BAC) clone RP23-401D9 containing the mouse Gt(ROSA)26Sor gene (and 153 kb of upstream and 15 kb of downstream sequence) was modified by inserting a red-shifted variant Enhanced Green Fluorescent Protein (EGFP; Clontech No. 6029-1) cDNA and polyadenylation sequence at nucleotide 521 of the first exon of transcript 1. Founders with a single copy of the transgene (founder line I1) were maintained on a CD-1 background. EGFP is ubiquitously and reproducibly expressed in all tissues and organs examined. Stable and uniform EGFP expression is observed in differentiated progeny of transplanted hematopoietic stem cells (HSC) isolated from ROSA26-EGFP mice. (J:126166)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available

Original:	J:126166 Giel-Moloney M, et al., Ubiquitous and uniform in vivo fluorescence in ROSA26-EGFP BAC transgenic mice. Genesis. 2007 Feb;45(2):83-9
All:	4 reference(s)