Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mapk1tm1.1Kuta
Name:	mitogen-activated protein kinase 1; targeted mutation 1.1, Kunio Takishima
MGI ID:	MGI:3759775
Synonyms:	Erk2-
Gene:	Mapk1  Location: Chr16:16801246-16865317 bp, + strand  Genetic Position: Chr16, 10.53 cM
Alliance:	Mapk1tm1.1Kuta page

Germline Transmission:	Earliest citation of germline transmission: J:125594
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 2 and 3 were removed by cre-mediated recombination following a cross to Tg(EIIa-cre)C5379Lmgd mice. (J:125594)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk1 Mutation:	40 strains or lines available

Original:	J:125594 Satoh Y, et al., Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory. J Neurosci. 2007 Oct 3;27(40):10765-76
All:	4 reference(s)