Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hdac6tm1Pmt
Name:	histone deacetylase 6; targeted mutation 1, Patrick Matthias
MGI ID:	MGI:3759271
Gene:	Hdac6  Location: ChrX:7796359-7814128 bp, - strand  Genetic Position: ChrX, 3.58 cM
Alliance:	Hdac6tm1Pmt page

Germline Transmission:	Earliest citation of germline transmission: J:132629
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted between exon 7 and 8 and an additional loxP site was inserted downstream of exon 10. Transient cre expression was used to remove the neo cassette by cre-mediated recombination. (J:132629)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hdac6 Mutation:	14 strains or lines available

Original:	J:132629 Zhang Y, et al., Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol. 2008 Mar;28(5):1688-701
All:	4 reference(s)