Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Fbn2fp-3J
Name:	fibrillin 2; fused phalanges 3 Jackson
MGI ID:	MGI:2157491
Synonyms:	Fbn2fp-3J, Fbn2fp-sne, sne
Gene:	Fbn2  Location: Chr18:58141689-58343200 bp, - strand  Genetic Position: Chr18, 32.15 cM, cytoband D-E1
Alliance:	Fbn2fp-3J page

Germline Transmission:	Earliest citation of germline transmission: J:60747
Parent Cell Line:	v6.4 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S4/SvJae)F1

Allele Type:    Chemically induced (other) Mutations:    Intragenic deletion, Transposon insertion   Mutation details: The 3' end of a LINE element, including an approximately 120-bp poly(A) tail, 657 bp of 3'UTR, and 61 amino acids from the 3' end of ORF2, replaced a 672 bp segment of the gene including 465 bp of the 3' end of intron 57, exon 58 in its entirety, and 81 bp of the 5' end of intron 59. (J:69450) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fbn2 Mutation:	142 strains or lines available

Original:	J:60747 Munroe RJ, et al., Mouse mutants from chemically mutagenized embryonic stem cells. Nat Genet. 2000 Mar;24(3):318-21
All:	2 reference(s)