Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Engtm2.2Hma
Name:	endoglin; targeted mutation 2.2, Helen M Arthur
MGI ID:	MGI:3712803
Synonyms:	Engdeltaex5-6
Gene:	Eng  Location: Chr2:32536607-32572681 bp, + strand  Genetic Position: Chr2, 22.09 cM
Alliance:	Engtm2.2Hma page

Germline Transmission:	Earliest citation of germline transmission: J:121898
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Exons 5 and 6 were removed from the locus by cre mediated recombination. (J:121898)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Eng Mutation:	41 strains or lines available

Original:	J:121898 Allinson KR, et al., Generation of a floxed allele of the mouse endoglin gene. Genesis. 2007 Jun;45(6):391-5
All:	2 reference(s)