Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Rnf2tm2Hko
Name:	ring finger protein 2; targeted mutation 2, Haruhiko Koseki
MGI ID:	MGI:3702691
Synonyms:	Ring1bfl
Gene:	Rnf2  Location: Chr1:151345149-151376747 bp, - strand  Genetic Position: Chr1, 64.15 cM
Alliance:	Rnf2tm2Hko page

Germline Transmission:	Earliest citation of germline transmission: J:94519
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 2, containing the ATG, was flanked with loxP sites. A neomycin resistance cassette and a third loxP site were inserted into intron 2. (J:94519)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rnf2 Mutation:	36 strains or lines available

Original:	J:94519 de Napoles M, et al., Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell. 2004 Nov;7(5):663-76
All:	5 reference(s)