Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxa1tm5Mrc
Name:	homeobox A1; targeted mutation 5, Mario R Capecchi
MGI ID:	MGI:3702593
Synonyms:	Hoxa1ARE(g)
Gene:	Hoxa1  Location: Chr6:52132573-52135299 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance:	Hoxa1tm5Mrc page

Germline Transmission:	Earliest citation of germline transmission: J:119279
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted Mutation:    Insertion   Mutation details: The 107 bp homeo box B1 autoregulatory enhancer was inserted into the endogenous promoter. An IREStauGFP cassette was also inserted into the locus, as well as an inversely oriented ACN self-excising neo selection marker. (J:119279)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa1 Mutation:	14 strains or lines available

Original:	J:119279 Tvrdik P, et al., Reversal of Hox1 gene subfunctionalization in the mouse. Dev Cell. 2006 Aug;11(2):239-50
All:	1 reference(s)