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Igltm1Bgmn
Targeted Allele Detail
Summary
Symbol: Igltm1Bgmn
Name: immunoglobulin lambda chain complex; targeted mutation 1, Marianne Bruggemann
MGI ID: MGI:3701003
Synonyms: C1-, ES1.3
Gene: Igl  Location: unknown  Genetic Position: Chr16, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118712
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted into C1 and a third loxP site was inserted 5' of C3. This resulted in silencing of C1. (J:118712)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igl Mutation:  3 strains or lines available
References
Original:  J:118712 Zou X, et al., Block in development at the pre-B-II to immature B cell stage in mice without Ig kappa and Ig lambda light chain. J Immunol. 2003 Feb 1;170(3):1354-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory