About   Help   FAQ
Foxo4tm1Rdp
Targeted Allele Detail
Summary
Symbol: Foxo4tm1Rdp
Name: forkhead box O4; targeted mutation 1, Ronald DePinho
MGI ID: MGI:3698869
Synonyms: Foxo4F, FoxO4L
Gene: Foxo4  Location: ChrX:100298134-100304479 bp, + strand  Genetic Position: ChrX, 43.89 cM
Alliance: Foxo4tm1Rdp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:118179
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 1 was flanked with loxP sites. This is the second major coding exon and encodes the C-terminal half of the full-length protein. (J:118179)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxo4 Mutation:  13 strains or lines available
References
Original:  J:118179 Paik JH, et al., FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 2007 Jan 26;128(2):309-23
All:  60 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory