Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tjp3tm1Mada
Name:	tight junction protein 3; targeted mutation 1, Makoto Adachi
MGI ID:	MGI:3697319
Synonyms:	ZO-3
Gene:	Tjp3  Location: Chr10:81109041-81127415 bp, - strand  Genetic Position: Chr10, 39.72 cM, cytoband C1
Alliance:	Tjp3tm1Mada page

Germline Transmission:	Earliest citation of germline transmission: J:117589
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 2-21 were replaced with a lacZ-neo cassette. Absence of transcript was confirmed by RT-PCR of mutant kidney. (J:117589)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tjp3 Mutation:	35 strains or lines available

Original:	J:117589 Adachi M, et al., Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein. Mol Cell Biol. 2006 Dec;26(23):9003-15
All:	1 reference(s)