Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gfi1tm1Wep
Name:	growth factor independent 1 transcription repressor; targeted mutation 1, William E Paul
MGI ID:	MGI:3696049
Synonyms:	Gfi1fex4-5, Gfi1fl
Gene:	Gfi1  Location: Chr5:107864521-107873671 bp, - strand  Genetic Position: Chr5, 52.23 cM
Alliance:	Gfi1tm1Wep page

Germline Transmission:	Earliest citation of germline transmission: J:117105
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exons 4 and 5 were flanked with loxP sites. (J:117105)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfi1 Mutation:	31 strains or lines available

Original:	J:117105 Zhu J, et al., Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18214-9
All:	17 reference(s)