Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trdmt1tm1Bes
Name:	tRNA aspartic acid methyltransferase 1; targeted mutation 1, Timothy H Bestor
MGI ID:	MGI:3695409
Synonyms:	Dnmt2-
Gene:	Trdmt1  Location: Chr2:13513825-13549479 bp, - strand  Genetic Position: Chr2, 10.0 cM, cytoband A1
Alliance:	Trdmt1tm1Bes page

Germline Transmission:	Earliest citation of germline transmission: J:104615
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: LoxP sites were introduced to flank exons 7-10 of the gene. Cre-mediated recombination resulted in deletion of exons 7-10.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trdmt1 Mutation:	37 strains or lines available

Original:	J:104615 Goll MG, et al., Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science. 2006 Jan 20;311(5759):395-8
All:	10 reference(s)