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Kcna5tm1Hket
Targeted Allele Detail
Summary
Symbol: Kcna5tm1Hket
Name: potassium voltage-gated channel, shaker-related subfamily, member 5; targeted mutation 1, Helmut Kettenmann
MGI ID: MGI:3694764
Synonyms: Kv1.5-
Gene: Kcna5  Location: Chr6:126509514-126512375 bp, - strand  Genetic Position: Chr6, 61.35 cM
Alliance: Kcna5tm1Hket page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116545
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe translational start site and most of the open reading frame was replaced with a neomycin resistance cassette. (J:116545)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcna5 Mutation:  34 strains or lines available
References
Original:  J:116545 Pannasch U, et al., The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia. Mol Cell Neurosci. 2006 Dec 15;33(4):401-411
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory