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Arctm1Stl
Targeted Allele Detail
Summary
Symbol: Arctm1Stl
Name: activity regulated cytoskeletal-associated protein; targeted mutation 1, Susumu Tonegawa
MGI ID: MGI:3694120
Synonyms: Arc-d2EGFP, Arc-GFP
Gene: Arc  Location: Chr15:74540932-74544419 bp, - strand  Genetic Position: Chr15, 34.25 cM
Alliance: Arctm1Stl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115255
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a d2EGFP-stop cassette and a floxed neo after the ATG start codon. Western blot confirmed absence of protein in mutant brain samples. (J:115255)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Arc Mutation:  25 strains or lines available
References
Original:  J:115255 Wang KH, et al., In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. Cell. 2006 Jul 28;126(2):389-402
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory