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Fbxo11Mutt
Chemically induced Allele Detail
Summary
Symbol: Fbxo11Mutt
Name: F-box protein 11; Mutt
MGI ID: MGI:3690632
Gene: Fbxo11  Location: Chr17:88298287-88372719 bp, - strand  Genetic Position: Chr17, 57.87 cM
Alliance: Fbxo11Mutt page
Mutation
origin
Strain of Origin:  (C3H/HeN x BALB/c)F1
Mutation
description
Allele Type:    Chemically induced (ENU) (Hypomorph)
Mutation:    Nucleotide substitutions
    This is a hypomorphic allele caused by a serine to leucine mutation at position 244 in exon 7. (J:114851)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fbxo11 Mutation:  51 strains or lines available
References
Original:  J:114851 Hardisty-Hughes RE, et al., A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. Hum Mol Genet. 2006 Nov 15;15(22):3273-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory