Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	bpck
Name:	bilateral polycystic kidney deletion region; bilateral polycystic kidneys
MGI ID:	MGI:3688712
Synonyms:	Tmem67bpck
Gene:	bpck  Location: unknown  Genetic Position: Chr4, Syntenic

Strain of Origin:

B6C3Fe a/a-tip/J

Allele Type:    Spontaneous Mutation:    Intergenic deletion   bpck involves 12 genes/genome features (Gm25002, 4932430A15Rik, Gm22477 ...) View all   Mutation details: This spontaneous deletion spans approximately 0.6 cM between D4Mit261 and D4Mit19, including the coding region of 6 genes, but the bilateral polycystic kidney phenotype was traced specifically to the absence of Tmem67 via BAC rescue with various length BACs. (J:144929) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any bpck Mutation:	1 strain or line available

Original:	J:144929 Cook SA, et al., A Mouse Model for Meckel Syndrome Type 3. J Am Soc Nephrol. 2009 Apr;20(4):753-64
All:	4 reference(s)