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Slc16a2tm1Sref
Targeted Allele Detail
Summary
Symbol: Slc16a2tm1Sref
Name: solute carrier family 16 (monocarboxylic acid transporters), member 2; targeted mutation 1, Samuel Refetoff
MGI ID: MGI:3687949
Synonyms: Mct82LoxP
Gene: Slc16a2  Location: ChrX:102741020-102865589 bp, - strand  Genetic Position: ChrX, 46.29 cM
Alliance: Slc16a2tm1Sref page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113732
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA vector containing a neo and tACE Cre recombinase flanked by loxP sites was inserted into intron 2 and a third loxP site was inserted into intron 3. The cre cassette excises itself upon passage through the germline, leaving exon 3 floxed. (J:113732)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc16a2 Mutation:  9 strains or lines available
References
Original:  J:113732 Dumitrescu AM, et al., Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice. Endocrinology. 2006 Sep;147(9):4036-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory