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Hprt1tm1(CUX1)Anep
Targeted Allele Detail
Summary
Symbol: Hprt1tm1(CUX1)Anep
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Alain Nepveu
MGI ID: MGI:3687214
Synonyms: Hprt1tm1(Cutl1)Anep
Gene: Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance: Hprt1tm1(CUX1)Anep page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113393
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Hprt1tm1(CUX1)Anep expresses 1 gene
 
Mutation detailsHuman CUTL1 (CUX1) p75 cDNA was inserted under the control of the MMTV promoter and placed into the Hprt locus. Two lines were created: 48 and 50. (J:113393)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:  1273 strains or lines available
References
Original:  J:113393 Cadieux C, et al., Transgenic Mice Expressing the p75 CCAAT-Displacement Protein/Cut Homeobox Isoform Develop a Myeloproliferative Disease-Like Myeloid Leukemia. Cancer Res. 2006 Oct 1;66(19):9492-501
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory