Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd79atm7Cgn
Name:	CD79A antigen (immunoglobulin-associated alpha); targeted mutation 7, University of Cologne
MGI ID:	MGI:3687010
Synonyms:	IgalphaY176,204F
Gene:	Cd79a  Location: Chr7:24596922-24601283 bp, + strand  Genetic Position: Chr7, 13.49 cM
Alliance:	Cd79atm7Cgn page

Germline Transmission:	Earliest citation of germline transmission: J:113407
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Not Specified) Mutation:    Nucleotide substitutions   Mutation details: A targeting vector was designed to allow for cre mediated replacement of exons 4 and 5, including the Y176F and Y204F mutations. (J:113407)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd79a Mutation:	22 strains or lines available

Original:	J:113407 Patterson HC, et al., The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain. Immunity. 2006 Jul;25(1):55-65
All:	1 reference(s)