Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mapk1tm2Hed
Name:	mitogen-activated protein kinase 1; targeted mutation 2, Stephen M Hedrick
MGI ID:	MGI:3686889
Synonyms:	Erk2-
Gene:	Mapk1  Location: Chr16:16801246-16865317 bp, + strand  Genetic Position: Chr16, 10.53 cM
Alliance:	Mapk1tm2Hed page

Germline Transmission:	Earliest citation of germline transmission: J:113280
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Disruption caused by insertion of vector     Exons 3 and 4 were replaced with a neomycin resistance cassette. (J:113280)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk1 Mutation:	40 strains or lines available

Original:	J:113280 Fischer AM, et al., The role of erk1 and erk2 in multiple stages of T cell development. Immunity. 2005 Oct;23(4):431-43
All:	1 reference(s)