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Gt(ROSA)26Sortm1(rtTA)Awu
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1(rtTA)Awu
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Anton Wutz
MGI ID: MGI:3664736
Synonyms: R26rtTA, Rosa26-rtRA-nls
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1(rtTA)Awu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:112954
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Transactivator)
Mutation:    Insertion
 
Mutation detailsA doxycycline-responsive transactivator cDNA with a nuclear localization signal was inserted via homologous recombination. (J:113196)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:112954 Savarese F, et al., Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol. 2006 Oct;26(19):7167-77
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory